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Effect of c-Met-mediated cell scatter on spot formation, tumor growth, and invasive morphology in high HGF conditions. (a) Stem cell distributions in HGF high conditions and without (ScOff, δ1,2 = 0.0) or with (ScOn, δ1,2 = 0.02) HGF-induced effect on cell scatter. (b) Quantification of stem scatter fraction (SSF) and shape factor (SF) for ScOff and ScOn simulations. Time-course data was smoothed using Moving Average Filtering in Matlab <t>R2014b.</t>
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Effect of c-Met-mediated cell scatter on spot formation, tumor growth, and invasive morphology in high HGF conditions. (a) Stem cell distributions in HGF high conditions and without (ScOff, δ1,2 = 0.0) or with (ScOn, δ1,2 = 0.02) HGF-induced effect on cell scatter. (b) Quantification of stem scatter fraction (SSF) and shape factor (SF) for ScOff and ScOn simulations. Time-course data was smoothed using Moving Average Filtering in Matlab <t>R2014b.</t>
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Effect of c-Met-mediated cell scatter on spot formation, tumor growth, and invasive morphology in high HGF conditions. (a) Stem cell distributions in HGF high conditions and without (ScOff, δ1,2 = 0.0) or with (ScOn, δ1,2 = 0.02) HGF-induced effect on cell scatter. (b) Quantification of stem scatter fraction (SSF) and shape factor (SF) for ScOff and ScOn simulations. Time-course data was smoothed using Moving Average Filtering in Matlab <t>R2014b.</t>
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Effect of c-Met-mediated cell scatter on spot formation, tumor growth, and invasive morphology in high HGF conditions. (a) Stem cell distributions in HGF high conditions and without (ScOff, δ1,2 = 0.0) or with (ScOn, δ1,2 = 0.02) HGF-induced effect on cell scatter. (b) Quantification of stem scatter fraction (SSF) and shape factor (SF) for ScOff and ScOn simulations. Time-course data was smoothed using Moving Average Filtering in Matlab R2014b.

Journal: Journal of theoretical biology

Article Title: Activation of the HGF/c-Met axis in the tumor microenvironment: a multispecies model

doi: 10.1016/j.jtbi.2017.11.025

Figure Lengend Snippet: Effect of c-Met-mediated cell scatter on spot formation, tumor growth, and invasive morphology in high HGF conditions. (a) Stem cell distributions in HGF high conditions and without (ScOff, δ1,2 = 0.0) or with (ScOn, δ1,2 = 0.02) HGF-induced effect on cell scatter. (b) Quantification of stem scatter fraction (SSF) and shape factor (SF) for ScOff and ScOn simulations. Time-course data was smoothed using Moving Average Filtering in Matlab R2014b.

Article Snippet: Time-course data was smoothed using Moving Average Filtering in Matlab R2014b.

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